Beauty,Health and Fitness: Lead Acetate is baned by FDA from Consumer Hair D...

Beauty,Health and Fitness: Lead Acetate is baned by FDA from Consumer Hair D...: FDA on Tuesday banned lead acetate from hair coloring products, a move prompted by petitions from consumer watchdog groups. The a...

Lead Acetate is baned by FDA from Consumer Hair Dyes

FDA on Tuesday banned lead acetate from hair coloring products, a move prompted by petitions from consumer watchdog groups.
The agency’s final rule means lead is now banned in all cosmetic products. Hair dye was the last product in which it was still allowed. Lead acetate is already banned in the European Union and in Canada.
“In the nearly 40 years since lead acetate was initially approved as a color additive, our understanding of the hazards of lead exposure has evolved significantly,” FDA Commissioner Scott Gottlieb, MD, says in a statement. “We now know that the approved use of lead acetate in adult hair dyes no longer meets our safety standard.”
The Environmental Working Group, one of a dozen groups that petitioned the FDA for the ban, said the decision is long overdue.
“There is no safe level of lead exposure,” Melanie Benesh, a legislative attorney at EWG, says in a statement.

 

Why Does Your Hair Go Gray?

 

 

Your first gray hair can be upsetting. So why does your hair lose its color as you age?

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Lead exposure can have serious health effects, especially for children. The EWG says it has been linked to developmental issues in children, reduced fertility, organ system toxicity, cancer, and other problems.
Most manufacturers had long ago moved to other additives for hair coloring, but a few continued to use lead. Manufacturers have 1 year from the effective date of the final rule to remove lead acetate from their products. Grecian Formula was one of the last major brands still to use lead acetate, but it, too, switched to another chemical, bismuth citrate, as a coloring agent.
“In the last several decades, we’ve seen tremendous progress in reducing exposure to lead from major sources. Given this progress and wide recognition that there is no safe level of exposure, it may seem unbelievable that common hair dyes contain the neurotoxin -- putting those who use the product and their children at risk,” says Tom Neltner, chemicals policy director at the Environmental Defense Fund, another group that petitioned the FDA to act.
The FDA did not provide a list of products that contain lead but says consumers should examine product labels. Lead, if included, would be listed as an ingredient.
The FDA says recent scientific data show there is “no longer a reasonable certainty that there is no harm from the use of lead acetate as a color additive.”

BEST DYES FOR GREY HAIR:

 

Are you starting to go gray and thinking of coloring your hair at home? If so, you have lots of options. Here's advice from Las Vegas celebrity stylist Michael Boychuck and cosmetics chemist Ni'Kita Wilson.
Michael Boychuck says:
Gray hair is especially vulnerable to the drying effects of chemicals in dye. That's why I suggest ammonia-free formulas. There is quite a selection out there, and most won't damage hair. I like the new Umberto Beverly Hills U Color and Revlon ColorSilk. Herbatint Permanent Herbal Haircolour Gel is another good option.
Another reason to avoid ammonia: color fade. Ammonia penetrates the outer cuticle layer to deposit color in the inner cortex of the hair, and often the cuticle can't recover completely. That means the color can leach out over time -- especially during a shampoo. When you wash, use a gentle, moisturizing shampoo to help limit the fading.
A leave-in conditioner is crucial. It's very important to shield your hair from the rays of the sun, styling damage, and dehydration to preserve the color. EverPure Moisture Leave-in Conditioner is a good option because it contains lightweight yet nourishing conditioners.

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Smart Live & Smart Living

With  Fashion Week well under way, we’ve noticed a significant pattern when it comes to what the street style stars are wearing: plaid. While parading down cobblestone streets in vertiginous high heels and posing in front of ornate wooden doors, they show us how to wear plaid right. Layer it under more plaid, pair it with a cosy sweater, or wear it with a mixed pattern; the right plaid skirt or trouser can add a touch of counterculture or prep to any outfit.

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Maroon 5 - Girls Like You ft. Cardi B (Volume 2)

Using fat to help wounds heal without scars

 

 

 

 

Breaking ground on method to transform cells

Date:

January 5, 2017

Source:

University of Pennsylvania School of Medicine

Summary:

Doctors have found a way to manipulate wounds to heal as regenerated skin rather than scar tissue. The method involves transforming the most common type of cells found in wounds into fat cells -- something that was previously thought to be impossible in humans.

 

This is a comparison of wounds healing with and without hair follicles.

Credit: Penn Medicine

Doctors have found a way to manipulate wounds to heal as regenerated skin rather than scar tissue. The method involves transforming the most common type of cells found in wounds into fat cells -- something that was previously thought to be impossible in humans. Researchers began this work at the Perelman School of Medicine at the University of Pennsylvania, which led to a large-scale, multi-year study in connection with the Plikus Laboratory for Developmental and Regenerative Biology at the University of California, Irvine. They published their findings online in the journal Science on Thursday, January 5th, 2017.

Fat cells called adipocytes are normally found in the skin, but they're lost when wounds heal as scars. The most common cells found in healing wounds are myofibroblasts, which were thought to only form a scar. Scar tissue also does not have any hair follicles associated with it, which is another factor that gives it an abnormal appearance from the rest of the skin. Researchers used these characteristics as the basis for their work -- changing the already present myofibroblasts into fat cells that do not cause scarring.
"Essentially, we can manipulate wound healing so that it leads to skin regeneration rather than scarring," said George Cotsarelis, MD, the chair of the Department of Dermatology and the Milton Bixler Hartzell Professor of Dermatology at Penn, and the principal investigator of the project. "The secret is to regenerate hair follicles first. After that, the fat will regenerate in response to the signals from those follicles."
The study showed hair and fat develop separately but not independently. Hair follicles form first, and the Cotsarelis lab previously discovered factors necessary for their formation. Now they've discovered additional factors actually produced by the regenerating hair follicle to convert the surrounding myofibroblasts to regenerate as fat instead of forming a scar. That fat will not form without the new hairs, but once it does, the new cells are indistinguishable from the pre-existing fat cells, giving the healed wound a natural look instead of leaving a scar. As they examined the question of what was sending the signal from the hair to the fat cells, researchers identified a factor called Bone Morphogenetic Protein (BMP). It instructs the myofibroblasts to become fat. This signaling was groundbreaking on its own, as it changed what was previously known about myofibroblasts.
"Typically, myofibroblasts were thought to be incapable of becoming a different type of cell," Cotsarelis said. "But our work shows we have the ability to influence these cells, and that they can be efficiently and stably converted into adipocytes." This was shown in both the mouse and in human keloid cells grown in culture.
"The findings show we have a window of opportunity after wounding to influence the tissue to regenerate rather than scar," said the study's lead author Maksim Plikus, PhD, an assistant professor of Developmental and Cell Biology at the University of California, Irvine. Plikus began this research as a postdoctoral fellow in the Cotsarelis Laboratory at Penn, and the two institutions have continued to collaborate.
These discoveries have the potential to be revolutionary in the field of dermatology. The first and most obvious use would be to develop a therapy that signals myofibroblasts to convert into adipocytes -- helping wounds heal without scarring.
"It's highly desirable from a clinical standpoint, but right now it's an unmet need," Cotsarelis said.
But the increase of fat cells in tissue can also be helpful for more than just wounds. Adipocyte loss is a common complication of other conditions, especially treatments for HIV, and right now there is no efficient strategy for treatment. The cells are also lost naturally because of the aging process, especially in the face, which leads to permanent, deep wrinkles, something anti-aging treatments can't fix in a cosmetically satisfactory way.
"Our findings can potentially move us toward a new strategy to regenerate adipocytes in wrinkled skin, which could lead us to brand new anti-aging treatments," Cotsarelis said.
The Cotsarelis Lab is now focusing on the mechanisms that promote skin regeneration, especially with respect to hair follicle regeneration.
The Plikus Laboratory is focusing on other aspects of cell reprogramming in skin wounds. Researchers there are examining the role of other signaling factory beyond BMP as well as conducting further studies using human cells and human scar tissue.

ACNE AND IT'S TREATMENTS

What is Acne?

There's a reason it's called "common acne" -- nearly everyone suffers from a pimple outbreak at some point in life.

It starts when greasy secretions from the skin's sebaceous glands (oil glands) plug the tiny openings for hair follicles (plugged pores). If the openings are large, the clogs take the form of blackheads: small, flat spots with dark centers. If the openings stay small, the clogs take the form of whiteheads: small, flesh-colored bumps. Both types of plugged pores can develop into swollen, tender inflammations or pimples or deeper lumps or nodules. Nodules associated with severe cases of acne (cystic acne) are firm swellings below the skin's surface that become inflamed, tender, and sometimes infected.

Although acne remains largely a curse of adolescence, about 20% of all cases occur in adults. Acne commonly starts during puberty between the ages of 10 and 13 and tends to be worse in people with oily skin. Teenage acne usually lasts for five to 10 years, normally going away during the early 20s. It occurs in both sexes, although teenage boys tend to have the most severe cases. Women are more likely than men to have mild to moderate forms into their 30s and beyond.

Acne lesions are most common on the face, but they can also occur on the neck, chest, back, shoulders, and upper arms.
Contrary to popular belief, acne isn't caused by a harmful diet, poor hygiene, or an uncontrolled sex drive. The simple truth is that heredity and hormones are behind most forms of acne. Swearing off chocolate or scrubbing your face 10 times a day won't change your predisposition to this unsightly, sometimes painful, and often embarrassing skin problem.

What Causes Acne?

The cause of acne is not fully understood. Though stress can aggravate acne, it clearly does not cause it.
Hormones. Common acne in teenagers starts with an increase in hormone production. During puberty, both boys and girls produce high levels of androgens, the male sex hormones that include testosterone. Testosterone signals the body to make more sebum, the oil produced in the skin's oil glands.

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What Are the Treatments for Acne?

The occasional pimple can be concealed. If used at all, over-the-counter cover-up creams and cosmetics should be water-based. Even if outbreaks of acne cannot be eliminated, conventional treatment can provide relief.
The best treatments inhibit sebum production, limit bacterial growth, or encourage shedding of skin cells to unclog pores. Because many therapies can have side effects, any patient with acne should proceed with caution when trying a new treatment. People with any type of acne that lowers their self-esteem or makes them unhappy, those with acne that is leaving scars or people with severe, persistent cases of acne, need the care of a dermatologist.

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Nonprescription Treatment for Acne

Soap and water. Gentle cleansing of the face with soap and water no more than two times a day can help with acne. However, this does not clear up acne that is already present. Aggressive scrubbing can injure the skin and cause other skin problems.
Cleansers. There are many cleansers and soaps advertised for treating acne. They often contain benzoyl peroxide, glycolic acid, salicylic acid, or sulfur.
Benzoyl peroxide. For mild acne, you may try, or your doctor may recommend, treatment with a nonprescription drug that contains benzoyl peroxide. It's believed that this compound works by destroying the bacteria associated with acne. It usually takes at least four weeks to work and it must be used continuously to keep acne at bay. Like many over-the-counter and prescription products, it does not affect sebum production or the way the skin follicle cells are shed, and when you stop using it, the acne comes back. It is available in many forms: creams, lotions, washes, and gels. Benzoyl peroxide can cause dry skin and can bleach fabrics, so take care when applying it. Consider wearing an old T-shirt to bed if you are applying it to your back or chest overnight.
Salicylic acid. On the skin, salicylic acid helps to correct the abnormal shedding of cells. For milder acne, salicylic acid helps unclog pores to resolve and prevent lesions. It does not have any effect on sebum production and does not kill bacteria. It must be used continuously, just like benzoyl peroxide, because its effects stop when you stop using it -- pores clog up again and the acne returns. Salicylic acid is available in many acne products, including lotions, creams, and pads.

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